Today, genetics offers great support to reproductive medicine, providing different tests depending on the reproductive stage in which the couple is.

Once IVF has been performed, Preimplantation Genetic Diagnosis (PGD or PGD) studies the genetic health of the embryos using different methods.

When is PGD recommended?

Normally, to perform a PGD there must be a prior indication from a specialist.

• Women over 35 years of age by age risk
• Recurrent abortions
• Repeated failures of previous treatments
• Repeated embryo implantation failures
• Couples who are symptomatic or asymptomatic carriers of dominant, recessive, numerical or structural genetic diseases
• Female carrier of an X-linked disease

Study the genetic health of embryos using different methods

When it ‘s made?

The PGD study must be performed on embryos generated in an IVF cycle. It is important to have an adequate number of embryos to find the embryos with the greatest implantation potential.

To perform PGD in Nido Fertility, the embryos are cultured strictly until the blastocyst stage, which is reached on day 5-6 after fertilization. At that time, the Embryonic Biopsy of the external layer also called trophectoderm, which will give rise to the placenta, is performed.

Embryo Biopsy is the technique that allows a small hole to be made in the trophectoderm of the embryo and 4-5 cells to be aspirated. Since these cells will give rise to the placenta, it does not affect the development of the embryo. Once the biopsy is performed, the embryo is vitrified or transferred into the uterus once the result of the analysis is known.

Genetic study of the embryo:

PGD ​​consists of analyzing the genetic status of the embryo. Biopsied samples of all embryos are studied in a genetics laboratory. Once the study is completed, the laboratory provides a report indicating the embryos that have the greatest implantation potential.

Thanks to Preimplantation Genetic Diagnosis we can prevent better-known diseases such as Down syndrome, but also many of the so-called rare diseases, and even some types of hereditary cancer.

Sex Selection:

With assisted reproduction treatment, today it is possible to choose the sex of your baby. In Nido Fertility, through ovarian hormonal stimulation, we obtain oocytes and these are inseminated with the male’s sperm to obtain embryos.

When we have the embryos, we perform a Preimplantation Genetic Diagnosis, which consists of a biopsy to obtain a cell and analyze the genetic information of that embryo and then introduce it into the mother’s uterus.